Recommended Links

Hamilton & Regional Sites

Point Juravinski Cancer Centre (JCC)
The Juravinski Cancer Centre (JCC) is the new name of one of eight Regional Cancer Centres of Cancer Care Ontario (CCO). Cancer Care Ontario was launched by the provincial government in 1997 to create and oversee a coordinated cancer care system. The agency sets direction and provides leadership for a broad range of services such as treatment, prevention, research and supportive care. CCO also sets standards to ensure that patients across the province receive the same high quality of care, regardless of where they live.
Point Hamilton Health Sciences
Hamilton Health Sciences is a family of five unique hospitals and a cancer centre, serving more than 2.2 million residents of Hamilton and Central South and Central West Ontario. Each hospital has specific areas of expertise and together, Hamilton Health Sciences is one of the most comprehensive health care systems in Canada. Through affiliation with McMaster University's Faculty of Health Sciences, they able to offer an academic environment where patients benefit from some of the most innovative treatments and are cared for by some of the most talented medical professionals in the country.
Point Department of Oncology, McMaster University
Point Link to Hamilton Health Sciences Research Ethics Board
Point McMaster University Research Ethics Board
Point St. Josephs Hamilton Research Ethics Board

Canadian Sites

Point National Cancer Institute of Canada Clinical Trials Group
This website provides information on clinical trials of new cancer therapies, supportive care and anti-cancer drugs being conducted by the Clinical Trials Group across Canada and internationally. The Clinical Trials Group is one of the national programs of the National Cancer Institute of Canada and is supported by funds raised by the Canadian Cancer Society.
Point Ontario Institute for Cancer Research
The Ontario Institute for Cancer Research is a not-for-profit organization funded by the Government of Ontario and set up to support and increase research that is focused on the development and testing of new cancer treatments.
Point Canadian College of Physicians and Surgeons Provincial Offices
This site provides direct links to all participating provincial colleges.

Canadian Regulatory Information Links

Point Health Canada
Health Canada is the Federal department responsible for helping Canadians maintain and improve their health, while respecting individual choices and circumstance.
Point Clinical trials FAQs
Point Clinical Trials Applications
Point Clinical Application and Attestation Form
Point Qualified Investigator Form
Point Clinical Trial Site Information Form
Point Adverse Drug Reactions Expedited Reporting Summary Form
Point Health Canadas Clinical Trials Manual
This manual is based on Health Canadas Guidance for Clinical Trial Sponsors: Clinical Trial Applications and other applicable guidance documents. It is designed to provide tools and relevant links in order to facilitate the successful filing of a Clinical Trial Application (CTA) to Health Canada. The information provided within this package is for clinical trials that involve the use of Pharmaceutical and/or Biological and Radiopharmaceutical drugs in human subjects. The information does not apply to clinical trials involving Medical Devices and Natural Health Products.
Point Health Canadas Clinical Trials Manual for trials involving Medical Devices

Ontario Links

Point Ontario Cancer Research Ethics Board
The Ontario Cancer Research Ethics Board (OCREB) works in collaboration with Ontario Institutions to ensure that research involving human subjects meets the highest standards of scientific and ethical conduct. OCREB is organized and operates according to the Tri-Council Policy Statement: Guidelines on Research Involving Human Subjects (TCPS); the International Conference on Harmonization (ICH) Good Clinical Practice (GCP) Consolidated Guideline; Part C, Division 5 of the Food and Drug Regulations of Health Canada; and the provisions of the Ontario Personal Health Information Protection Act 2004 (PHIPA) and its applicable regulations.
OCREB Forms
OCREB Guidelines and Templates
Point Cancer Care Ontario
Cancer Care Ontario is an umbrella organization that steers and coordinates Ontario's cancer services and prevention efforts so that fewer people get cancer, and patients receive the highest possible quality of care. As the provincial governments chief cancer advisor, Cancer Care Ontario directs over $500-million in public funding for cancer prevention, detection and care. The agency also operates screening and prevention programs; collects, monitors and reports information about cancer system performance; develops evidence-based standards and guidelines; and works with regional providers to plan and improve services for patients.
Point College of Physicians and Surgeons of Ontario
The College of Physicians and Surgeons of Ontario (CPSO) is the self-regulating body for the province's medical profession. The College regulates the practice of medicine to protect and serve the public interest. It issues certificates of registration to doctors to allow them to practise medicine, monitors and maintains standards of practice through peer assessment and remediation, investigates complaints against doctors on behalf of the public, and disciplines doctors
who may have committed an act of professional misconduct or incompetence.

Trial Registries

Point ClinicalTrials.gov
ClinicalTrials.gov provides regularly updated information about federally and privately supported clinical research in human volunteers. ClinicalTrials.gov gives you information about a trial's purpose, who may participate, locations, and phone numbers for more details.
Point OntarioCancerTrials.ca
Developed by the Ontario Institute for Cancer Research, this website contains a complete list of cancer treatment and cancer prevention trials in Ontario. Patients and their doctors can find trials according to type of cancer by location throughout the province with an easy-to-use search function. The site also provides information about the clinical trial process.

International Sites

Point U.S. Food & Drug Administration
The Food and Drug Administration (FDA) is an agency of the United States Department of Health and Human Services and is responsible for regulating food, dietary supplements, drugs, biological medical products, blood products, medical devices, radiation-emitting devices, veterinary products, and cosmetics in the United States.
Point US National Cancer Institute
This site provides easy-to-understand information about clinical trials going on around the world many of them in Canada and includes full-text publications and links to many other relevant sites. Information is tailored for patients or for health professionals.
Point The NIH Clinical Center
The NIH Clinical Center in Bethesda, Maryland is the research hospital of the National Institutes of Health (NIH).

Information on Clinical Trials

Point ICH Good Clinical Practice Guidelines
The International Conference on Harmonization of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH) is a unique project that brings together the regulatory authorities of Europe, Japan and the United States and experts from the pharmaceutical industry in the three regions to discuss scientific and technical aspects of product registration.
Point Tri-Council Policy Statement: Ethical Conduct for Research Involving Humans
This Tri-Council Policy Statement: Ethical Conduct for Research Involving Humans (TCPS) describes the policies of the Canadian Institutes of Health Research (CIHR), the Natural Sciences and Engineering Research Council of Canada (NSERC), and the Social Sciences and Humanities Research Council of Canada (SSHRC).
Point Direct link to current TCPS PDF file
Point Online TCPS tutorial
This tutorial for the TCPS helps to educate the research community about the TCPS. It also facilitates the use, interpretation and implementation of the TCPS.
Point The NIH Office of Extramural Research and the NIH Inter-Institute Bioethics Interest Group
The NIH Office of Extramural Research (OER) and the NIH Inter-Institute Bioethics Interest Group provides information on policies and regulations, Research Ethics Board resources, guidance for clinical investigators, research resources, courses and tutorials on bioethical issues in human studies
Point Health Canadas Clinical Trials Manual for trials involving Natural Health Products
Point NCI Common Terminology Criteria for Adverse Events v3.0 (CTCAE) (Version date: March 31, 2003)

Publications

Point U.S. National Library of Medicine
The U.S. National Library of Medicine (NLM) compiled a comprehensive bibliography from 1989 through November 1998, "Ethical Issues in Research Involving Human Participants," compiled by the National Library of Medicine:
Point PubMed
PubMed is a service of the U.S. National Library of Medicine that includes over 16 million citations from MEDLINE and other life science journals for biomedical articles back to the 1950s. PubMed includes links to full text articles and other related resources.
Point MedlinePlus
MedlinePlus is a web-based information service from the National Library of Medicine. Its Health Topics section has extensive information from NIH and other trusted sources on over 550 diseases and conditions, including a link to clinical trials. It also includes an informative "Clinical Trials" health topic page and an interactive tutorial on clinical trials.

Ontario Clinicians

Point Intute: Health and Life Sciences
Intute: Health and Life Sciences is the subject group of Intute that provides web resources for education and research for the following subjects:
    Medicine
    Nursing, Midwifery and Allied Health
    Agriculture, Food and Forestry
    Veterinary Medicine
    Bioresearch
    Natural history

Granting Agencies

Point Canadian Institutes of Health Research
Canadian Institutes of Health Research (CIHR) is the major federal agency responsible for funding health research in Canada. It aims to excel in the creation of new health knowledge, and to translate that knowledge from the research setting into real world applications. The results are improved health for Canadians, more effective health services and products, and a strengthened Canadian health care system.
Point CIHR Web Forms

Other Useful Links

Point Stedmans online medical dictionary
Point Cancer Care Ontarios Program in Evidence-based Care
Program in Evidence-based Care (PEBC) produces high-quality evidence-based series and practice guideline reports using the methods of the Practice Guidelines Development Cycle.