4D

D-Dimer testing, tailored to clinical pretest probability, to minimize initial and follow-up ultrasound imaging in suspected deep vein thrombosis: A management study (Designer D-dimer DVT Diagnosis [4D] Study)

Principal Investigator(s): Dr. Clive Kearon

ABOCA2

Investigation of the Anti-Cancer Activity of Artichoke Extract in an Asbestos-Exposed Population: The ABOCA Phase II Trial

Principal Investigator(s): Dr. Paola Muti

C-TRACT

Chronic Venous Thrombosis: Relief with Adjunctive Catheter Directed Therapy (C-TRACT Trial)

Principal Investigator(s): Dr. Clive Kearon, Dr. Suresh Vedantham

CANIMPACT

Improving Cancer Care Together through eOncoNote

Principal Investigator(s): Dr. Eva Grunfeld

COPE

Cannabis Oil for Pain Effectiveness

Principal Investigator(s): Dr Edward Chow, Dr. Marissa Slaven

LUSTRE

A Randomized Trial of Medically-Inoperable Stage I Non-small Cell Lung Cancer Patients Comparing Stereotactic Body Radiotherapy Versus Conventional Radiotherapy

Principal Investigator(s): Dr. Anand Swaminath, Dr. Tim Whelan

PETABC

Impact of 18F-FDG PET-CT versus Conventional Staging in the Management of Patients Presenting with Clinical Stage III Breast Cancer (PET ABC)

Principal Investigator(s): Dr. Andrea Eisen, Dr. Ian Dayes, Dr. Ralph George, Dr. Ur Metser

PETMUSE

Impact of Positron Emission Tomography (PET) Imaging in Muscle-invasive Urothelial Carcinoma of the Bladder Staging

Principal Investigator(s): Dr. Nicholas Power, Dr. Som Mukherjee, Dr. Srikala (Kala) Sridhar, Dr. Ur Metser

PRECISE

A Phase III Multi-centre Open-label Randomized Controlled Trial of Multi-Parametric Magnetic Resonance Imaging (MRI) Targeted Biopsy Compared to TRUS Guided Biopsy for the Diagnosis of Prostate Cancer in Men without Prior Biopsy.

Principal Investigator(s): Dr. Andrew Loblaw, Dr. Laurence Klotz, Dr. Masoom Abbas Haider

ALMERA

A Phase II Study to Investigate a Combination of Metformin with Chemo-Radiotherapy in Patients with Locally Advanced NSCLC

Principal Investigator(s): Dr. Theos Tsakiridis

DUCHESS

Evaluation of the Ductal Carcinoma in Situ Score for Decisions on Radiotherapy in Patients with Low/Intermediate Risk DCIS

Principal Investigator(s): Dr. Eileen Rakovitch, Dr. Tim Whelan

LUMINA

A Prospective Cohort Study Evaluating Risk of Local Recurrence Following Breast Conserving Surgery and Endocrine Therapy in Low Risk Luminal A Breast Cancer

Principal Investigator(s): Dr. Sally Smith, Dr. Tim Whelan

MISTER

Assessment of New Molecular Imaging Strategies for Prostate Cancer: Predictive Value of Established and Novel PET Radiotracers in Castration Resistant Prostate Cancer

Principal Investigator(s): Dr. Eric Winquist, Dr. Katherine Zukotynski

OPAR

A Phase II Randomized Trial of Radiation Fractionation Schedules for Once-a-Day Accelerated Partial Breast Irradiation

Principal Investigator(s): Dr. Do-Hoon Kim

PETLACE

The Impact of Positron Emission Tomography (PET) Imaging in Women with Locally Advanced Cervical Cancer

Principal Investigator(s): Dr. Anthony William Fyles, Dr. Laurie Elit