ADVANCE_HCC

Neoadjuvant Combination of Atezolizumab/Bevacizumab Versus Neoadjuvant Radiation Therapy Prior to Hepatectomy in Hepatocellular Carcinoma with Portal Vein Tumour Thrombus

Principal Investigator(s): Dr. Anand Swaminath, Dr. Brandon Meyers, Dr. Pablo Serrano

C-TRACT

Chronic Venous Thrombosis: Relief with Adjunctive Catheter Directed Therapy (C-TRACT Trial)

Principal Investigator(s): Dr. Sameer Parpia, Dr. Suresh Vedantham

CYTOSHRINK

Cytoreductive Stereotactic Hypofractionated Radiotherapy with Combination Ipilimumab/Nivolumab for Metastatic Kidney Cancer

Principal Investigator(s): Dr. Aly-Khan Lalani

ELISA

Prospective Evaluation of Breast-Conserving Surgery Alone in Low-Risk Ductal Carcinoma in Situ Defined by a Molecular Expression Assay Combined with Clinico-Pathological Features

Principal Investigator(s): Dr. Eileen Rakovitch, Dr. Tim Whelan

RHEAL

Randomized Trial of Hypofractionated LocoRegional Radiotherapy in Breast Cancer and Lymphedema

Principal Investigator(s): Dr. Tim Whelan

LUMINA

A Prospective Cohort Study Evaluating Risk of Local Recurrence Following Breast Conserving Surgery and Endocrine Therapy in Low Risk Luminal A Breast Cancer

Principal Investigator(s): Dr. Sally Smith, Dr. Tim Whelan

OPAR

A Phase II Randomized Trial of Radiation Fractionation Schedules for Once-a-Day Accelerated Partial Breast Irradiation

Principal Investigator(s): Dr. Do-Hoon Kim

PETABC

Impact of 18F-FDG PET-CT versus Conventional Staging in the Management of Patients Presenting with Clinical Stage III Breast Cancer (PET ABC)

Principal Investigator(s): Dr. Andrea Eisen, Dr. Ian Dayes, Dr. Ralph George, Dr. Ur Metser

PETMUSE

Impact of Positron Emission Tomography (PET) Imaging in Muscle-invasive Urothelial Carcinoma of the Bladder Staging

Principal Investigator(s): Dr. Nicholas Power, Dr. Som Mukherjee, Dr. Srikala (Kala) Sridhar, Dr. Ur Metser

PRECISE

A Phase III Multi-centre Open-label Randomized Controlled Trial of Multi-Parametric Magnetic Resonance Imaging (MRI) Targeted Biopsy Compared to TRUS Guided Biopsy for the Diagnosis of Prostate Cancer in Men without Prior Biopsy.

Principal Investigator(s): Dr. Andrew Loblaw, Dr. Laurence Klotz, Dr. Masoom Abbas Haider